State Based Model of Long-Term Potentiation and Synaptic Tagging and Capture

doi:10.1371/journal.pcbi.1000259

State Based Model of Long-Term Potentiation and Synaptic Tagging and Capture

Figure 7

Theoretical mean and fluctuations in the synaptic strength.

(A) The time course of the expected value of the fEPSP for a population of 1000 synapses, given either weak HFS (blue, upper curve) or weak LFS (red, lower curve), administered at time . (B) The corresponding standard deviation of the fEPSP as a function of time. The fluctuation increases for e-LTP and decreases for e-LTD. (C,D) Analogous plots for a population given strong HFS or strong LFS; in this case the fluctuations decrease for both protocols.

doi: https://doi.org/10.1371/journal.pcbi.1000259.g007