State Based Model of Long-Term Potentiation and Synaptic Tagging and Capture
Figure 6
(A) Weak HFS at followed by weak LFS at
to same population leads to de-potentiation. (B) Weak HFS at
followed by weak LFS at
. In this case e-LTP is not reversed by the LFS; it has become immune to depotentiation. (C) Pop. 1 is given weak HFS at
followed by weak LFS at
, and pop. 2 is given strong HFS at
. Pop. 1 remains stable at baseline after the stimuli, while pop. 2 exhibits
. (D) Pop. 1 is given weak HFS at
followed by weak de-potentiation LFS at
, and pop. 2 is given strong HFS at
. In this instance both populations exhibit
.