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Questioning the Ubiquity of Neofunctionalization

Figure 7

Triangles and connected triples in gene duplication.

(A) The network has T = 1 triangle and Γ = 5 connected triples. (B) Simple duplication adds a duplicate of the progenitor's single triangle to the network. There are γp = kp(kp−1)/2 = 3 connected triples centered around the progeny, and an additional Σkg = 5 connected triples centered on the neighbors. (C) If the progenitor is self-interacting, an additional edge between the progenitor and progeny is formed, thus increasing the simple duplication counts by kp = 3 additional triangles (extruded for clarity) and 2kp additional connected triples (the progenitor and progeny are both centered on kp additional connected triples due to the dimerizing interaction).

Figure 7

doi: https://doi.org/10.1371/journal.pcbi.1000252.g007