Dynamic Correlation between Intrahost HIV-1 Quasispecies Evolution and Disease Progression
Figure 9
Dynamics of synonymous and nonsynonymous evolutionary rates.
Synonymous (blue lines) and nonsynonymous (black lines) evolutionary rates as a function of the distance from the root of the tree for 9 patients from Ref. [13]. Synonymous and nonsynonymous rates were calculated using maximum likelihood trees based on only synonymous and non-synonymous substitutions, respectively, which were inferred using HyPhy with optimized MG94xREV models [30].