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Dynamic Correlation between Intrahost HIV-1 Quasispecies Evolution and Disease Progression

Figure 5

Dynamics of divergence and diversity with fitness reduction.

Dynamics of divergence and diversity when fitness is reduced to 50% of its original value for d>dc = 50 mutations. For d≤50, f = 1 and for d>50, f = 0.5, and M(d) = 0.5 for all d. The saturation of divergence and the decrease of diversity are observed.

Figure 5

doi: https://doi.org/10.1371/journal.pcbi.1000240.g005