Dynamic Correlation between Intrahost HIV-1 Quasispecies Evolution and Disease Progression
Figure 4
Dynamics of divergence and diversity with linear increase of fitness profile.
Divergence (A) and diversity (B) as a function of time for f(d) = f1+f2d and M(d) = m [submodel 1] for different values of f2/f1. The value of m is chosen as 0.5 and f1 = 1. The scale factors 300 and 20 for the divergence and the diversity are introduced to make comparable to the absolute values of measured divergence and diversity. Divergence (C) and diversity (D) as a function of time for f(d) = f1+f2d and M(d) = 1−d/dmax for d≤dmax and M(d) = 0 for d>dmax [submodel 2]. The value of dmax is 40 and f1 = 1. The scale factor for the divergence is 500 and that for the diversity is 50.