Dynamic Correlation between Intrahost HIV-1 Quasispecies Evolution and Disease Progression
Figure 2
Two measures of diversity dynamics of 9 longitudinally followed patients.
Diversity dynamics of each subject from the definition of average pairwise distance [red line] among all the sequences sampled at the same time point and the standard deviation [blue line] of the distribution of the tree distances of all the sequences at the same time point from the founder strain multiplied by a constant factor. The constant factors are 20, 20, 25, 25, 27, 40, 40, 30, 70 for S-P1 to S-P11, respectively. The two measures of diversity are proportional to each other.