Identifying the Important HIV-1 Recombination Breakpoints
Figure 2
The significance of local sequence identity to recombination.
The main plot displays the normalized distribution of in vitro breakpoints falling within zones ranging from size 1 to 25 (vertical grey bars); see Baird et al. [21] for further details. The horizontal lines indicate the expected random distribution of breakpoints for the zones. The inset plot shows the normalised frequency of both the in vitro breakpoints and randomly generated breakpoints for zones up to size 25 (arranged in groups of five). On the main plot, error bars on the random distributions (vertical lines) represent one standard error to include 68.3% of the distribution. On the inset, the error bars on the random distributions represent 1.96×standard error to include 95% of the distribution.