Why Do Hubs in the Yeast Protein Interaction Network Tend To Be Essential: Reexamining the Connection between the Network Topology and Essentiality
Figure 6
Enrichment of ECOBIM and non-ECOBIM hubs in essential proteins.
Fraction of essential proteins among various types of hubs: all hubs, hubs that are members of ECOBIMs (ECOBIM hubs), and hubs that are not members of ECOBIMs (non-ECOBIM hubs). The fraction of essential proteins among all proteins in the network is also shown (ntwk.avg.). The numbers above the bars show the number of essential hubs out of the total number of hubs of this type for ECOBIM and non-ECOBIM hubs.