Why Do Hubs in the Yeast Protein Interaction Network Tend To Be Essential: Reexamining the Connection between the Network Topology and Essentiality
Figure 3
Vulnerability to attack against most central proteins.
(A–F) The impact of node removal is quantified by the fraction of nodes in the largest connected component. There is one curve for each centrality measure that shows the fraction of nodes in the largest connected component as a function of the fraction of the most central nodes removed. We also show the impact of node removal in a random order and the size of the largest connected component when all essential proteins are removed.