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Allosteric Communication in Myosin V: From Small Conformational Changes to Large Directed Movements

Figure 9

The rigor-like to NMSM post-rigor conformational transition.

The energy-minimized rigor structure is color-coded as in Figure 2. The NMSM post-rigor conformation (referred to as in the text) is shown in grey. The subdomain screw axes used to describe the transition in terms of individual subdomain rigid-body motions (see Table 3 and Text S4) are indicated; the screw axis corresponding to the C subdomain, ĉ, is omitted for clarity and shown in Figure 10E.

doi: https://doi.org/10.1371/journal.pcbi.1000129.g009