Active Nuclear Receptors Exhibit Highly Correlated AF-2 Domain Motions
Figure 5
Quasiharmonic and Normal Mode Analyses.
Angles between motion vectors for all residue pairs in the PXR-RXR heterodimer and heterotetramer. Motion vectors were identified by quasiharmonic analysis (QHA, using the first two modes; (A) and by normal mode analysis (NMA, using the first 14 nontrivial modes; (B). In the plots, green represents angles close to zero (correlated), while yellow indicates angles close to 180° (anticorrelated).