The Ascent of the Abundant: How Mutational Networks Constrain Evolution
Figure 8
Calculation of the contiguity statistic.
(A) Sample calculations of the contiguity statistic for three 18-mer shapes. (B) The contiguity statistic is strongly correlated with abundance for all lengths of RNA molecules studied; example shown is the 18-mer land-scape (r2 = 0.69, P<2.2×10−16). Minimal Gaussian noise was added to reduce granularity in the data.