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The Ascent of the Abundant: How Mutational Networks Constrain Evolution

Figure 6

Stochastic evolutionary simulation in the 12-mer fitness landscape.

(A) The phenotype abundance of the target strongly affects the success of adaptation (r = 0.76, P = 2.2×10−4). (B) The phenotype abundance at the start of the simulation has no effect on the evolutionary outcome (r = −0.023, P = 0.17). We simulated adaptation over one million generations with a genomic mutation rate of U = 0.0003 and a constant population size of N = 1000.

Figure 6

doi: https://doi.org/10.1371/journal.pcbi.1000110.g006