Unraveling Protein Networks with Power Graph Analysis
Figure 2
Two catalytic alpha subunits (CKA1, CKA2) and two regulatory beta subunits (CKB1, CKB2) interacting with the FACT complex, with sub-complex NIP1-RPG-PRT1, and with the PAF1 complex. The graph representation (A) consists of 80 edges whereas the power graph representation (B) has 30 power edges, thus an edge reduction of 62%. This simplification of the representation makes the separation of the regulatory subunits from the catalytic subunits immediately apparent without loss of information on individual interactions.