Quantitative Predictions of Peptide Binding to Any HLA-DR Molecule of Known Sequence: NetMHCIIpan
Figure 4
Prediction of Endogenously Presented Peptides.
The benchmark data set consists of 584 HLA-DR restricted ligands covering 28 HLA-DR alleles downloaded from the SYFPEITHI database as described in the text. For alleles not covered by the TEPITOPE method, the closest allele covered by the TEPITOPE method as identified by sequence similarity between the HLA pseudo-sequences is used. TEPITOPE Alleles give the average AUC performance over the 17 alleles covered by the TEPITOPE method, and non-TEPITOPE Alleles give the average AUC performance over the 11 alleles not covered by the TEPITOPE method (data for the individual alleles is given in Table S3).