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Circadian Phase Resetting via Single and Multiple Control Targets

Figure 4

Multiple input control.

Closed-loop phase resetting dynamics for dual ((A) and (B)), and triple ((C) and (D)) control targets are shown with respect to the initial phase difference (x-axis) and the initial condition (y-axis). The phase recovery time is denoted by the intensity of the color at each given data point: the lighter the color, the longer the recovery time. The mapping of color intensity to the recovery time (in hours) is reflected in the color bar. Each color bar is calibrated according to a minimum recovery time of 0 hours and maximum of 60 hours. (A) νs and νm Dual Control Targets (B) νs and KI Dual Control Targets (C) νs, νm, and KI Triple Control Targets (D) νm, νd, and k2 Triple Control Targets.

Figure 4

doi: https://doi.org/10.1371/journal.pcbi.1000104.g004