Context-Specific Metabolic Networks Are Consistent with Experiments
Figure 5
Metabolic engineering strain consistency score.
The normalized consistency score for an E. coli strain designed to produce lactate indicate that the Δpta ΔadhE strain has a metabolic gene expression state consistent with the simultaneous production of lactate and growth when compared with the wild-type. This higher normalized consistency score indicates that the gene expression data from the double deletion strain is more consistent with the metabolic engineering objective than the wild-type strain, in accordance with experimental measurements.