Computational and Experimental Analysis of Redundancy in the Central Metabolism of Geobacter sulfurreducens
Figure 6
Central Metabolism in G. sulfurreducens Showing the Alternative Metabolic Pathways Studied (Dotted/Dashed Lines)
The metabolic pathway in G. sulfurreducens after the refinement of the network based on the comparison of the in silico predictions with the physiological data from the mutant strains is shown. The underlined reactions represent cases for which the maximum allowed flux was constrained to the wild type levels. The boxes around the enzyme names highlight those proteins that were eliminated. The reactions with the “X” are constrained to have zero flux. Abbreviations are explained in Table S4.