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Computational and Experimental Analysis of Redundancy in the Central Metabolism of Geobacter sulfurreducens

Figure 4

Growth Curves for Wild Type Strain

(A) WT, (B) POR1, pyruvate ferredoxin oxidoreductase; (C) PPCK1, phosphoenolpyruvate carboxylase; (D) MDH1, malate dehydrogenase; (E) PTA1, phosphotransacetylase; (F) ATO1, acetyl-CoA transferase 1; (G) ATO2, acetyl-CoA transferase 2; (H) ATO3, acetyl-CoA transferase 1 and 2 mutant strains grown in medium containing fumarate as the electron acceptor, and acetate (•), acetate and hydrogen (), pyruvate (), pyruvate and hydrogen (▴), acetate and pyruvate (), or acetate, pyruvate, and hydrogen () as electron donors. Growth was measured at A600 over time. Data are means of triplicates.

Figure 4

doi: https://doi.org/10.1371/journal.pcbi.0040036.g004