Co-Regulation of Metabolic Genes Is Better Explained by Flux Coupling Than by Network Distance
Figure 3
The Effect of Flux Coupling and Network Distance on Operonic Organization in E. coli
(A) The fraction of intra-operonic gene pairs correlates with the type of flux coupling. The dashed baseline indicates the fraction of intra-operonic gene pairs expected by chance.
(B) The effect of flux coupling on the fraction of intra-operonic gene pairs in different network distance groups: χ2d=1 = 715.3, χ2d=2,3,4 = 5347.3, χ2d≥5 = 5022.3, d.f. = 2, and p < 10−155.