A Generic Mechanism for Adaptive Growth Rate Regulation
Figure 4
Adaptation Process over Several Environmental Conditions
(A) Time series of protein expressions xi(t) when the environmental condition is altered. The environmental conditions, i.e., substrates having nonzero Yi, are changed at time points indicated by arrows.
(B) Change of growth rate vg in the same time interval as (A). After the environmental changes, both expression levels of all proteins and the growth rate start to fluctuate until the cell finds a state of protein expression that realizes a high growth rate. In the simulation, the noise amplitude σ = 0.2.