An Evolutionary-Network Model Reveals Stratified Interactions in the V3 Loop of the HIV-1 Envelope
Figure 5
A consensus network assembled from edges with marginal posterior probabilities exceeding 0.95, in which nodes represent nonsynonymous substitution events at codon sites in the V3 and C4 domains. Nodes that correspond to residues in the C4 domain are shaded blue (numbered according to their position in the consensus env gene sequence), and nodes that were connected by strongly supported edges in the V3-specific network are shaded black. We retain the same numbering scheme for residues in V3 for consistency.