Stochastic Noise and Synchronisation during Dictyostelium Aggregation Make cAMP Oscillations Robust
Figure 2
Deterministic and Stochastic Simulations for the Same Worst Case Parameter Combinations Are Performed
The numbers of molecules are sampled with a 0.1 s interval for 10 h, and the distribution of each molecular species is compared. To avoid influences from the initial transient response, only the samples obtained after 5 h are considered when plotting the distributions. The inset of (E) is the distribution for the external cAMP. The noise effect is clearly significant in terms of generating oscillations.