A Nucleosome-Guided Map of Transcription Factor Binding Sites in Yeast
Figure 4
Nucleosome Occupancy and the Values of S℘D℘N℘ over Four Intergenic Sequences
(A) iYDR190C in Cbf1_SM, (B) iYAR007C in Mbp1_H2O2Hi, (C) YJLWdelta16 in Gcr1_YPD, and (D) iYBR043C in Gcn4_YPD. The boxes indicate binding sites annotated by Harbison et al. [2]. S℘D℘N℘ at the locations of each of these binding sites has a high value relative to the rest of the sequence regardless of the S℘N℘ score at those sites. In particular, in spite of the low accessibility at the binding sites of Gcr1 (in YJLWdelta16) and Gcn4 (in iYBR043C), S℘D℘N℘ correctly indicates a high prior probability at those regions.