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Self-organizing Mechanism for Development of Space-filling Neuronal Dendrites

Figure 8

Two Distinctive Branching Patterns of Real Neurons

(A,B) Smooth and well-aligned type. A neuron in thalamic nuclei in monkey (A) and Purkinje cell at postnatal day 25 (B).

(C,D) Rugged and less-aligned type. A neuron of inferior olivary complex of monkey (C) and a remodeled class I da neuron at a pupal stage, which was visualized with ppk-GAL4 UAS-mCD8::GFP [49] (D). Images in (A and C) were taken from [50].

(E) Quantification of DOB in the generated patterns in our computer simulation. Data are presented as the means ± SD. A single asterisk indicates p < 0.01 (t-test), and double asterisks indicate p < 0.001 (t-test).

Figure 8

doi: https://doi.org/10.1371/journal.pcbi.0030212.g008