Are There Rearrangement Hotspots in the Human Genome?
Figure 5
Breakpoint Re-Use Rate as a Function of θ, the Proportion of the Elements Deleted
(A) Breakpoint re-use rate for parameters n = 100 (m = 5, 12, 20, 32, and 48) and n = 1,000 (m = 50, 120, 200, 320, and 480), where n stands for the number of elements (genes) and m stands for the number of reversals. Since we reproduced simulations in [7], this figure and Figure 1 from [7] are identical. Detailed description (including pseudocode) of this simulation is given in [20].
(B) Breakpoint re-use rate for parameters n = 25,000 (m = 50, 120, 200, 320, and 480).