Are There Rearrangement Hotspots in the Human Genome?
Figure 2
A 2-break on edges (u,v) and (x,y) corresponding to (A) reversal: the edges belong to the same black-obverse cycle that is rearranged after 2-break; (B) fission: the edges belong to the same black-obverse cycle that is split by 2-break; and (C) translocation/fusion: the edges belong to different black-obverse cycles that are joined by 2-break.