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From Inverse Problems in Mathematical Physiology to Quantitative Differential Diagnoses

Figure 8

Transient Behavior of Continuous Time Cardiac Model

Temporal evolution of actual stroke volume of continuous time system during initial transient of simulation shown in Figure 5 (solid line) and stroke volume calculated from systolic and end-diastolic volumes that would occur if the discrete dynamical system was advanced one step from the current values given by the continuous system (dashed line). Note that the state of the continuous system rapidly approaches a fixed point of the discrete dynamical system, resulting in superposition of the two curves. The transient is caused by starting integration with a non-equilibrium distribution of fluid between arterial and venous compartments.

Figure 8

doi: https://doi.org/10.1371/journal.pcbi.0030204.g008