Structure-Templated Predictions of Novel Protein Interactions from Sequence Information
Figure 2
Predicted Interactions Verified by IP-MS
Immunoaffinity purification of bait proteins complexes followed by mass spectrometry identification of associated proteins confirmed 37 predicted interactions. Predictions between proteins that were both co-purified with the tagged bait protein (i.e., both proteins were prey) were not considered validated. Proteins are coloured according to their Gene Ontology biological process annotation.