Functional Representation of Enzymes by Specific Peptides
Figure 1
The Occurrence of Specific Peptides within the EC Hierarchy of Enzymes
(A) A sketch of the EC hierarchy and the assignments of SPs to SP classes. SPs can be compared with those appearing in Figure 1B.
(B) Aligned sequences of two groups of enzymes of level 4 that share the same third-level assignment. Alignment is performed according to SPs. The organisms in the upper group, 5.1.3.20, belong to proteobacteria, while those of the lower group, 5.1.3.2, also contain eukaryotes (ARATH, CYATE, and PEA). Boldfaced substrings denote SPs. Amino acids flanked by spaces denote active sites and binding sites, as indicated above. A list of all SPs and their assignments to SPN classes is presented below the sequences.