Elucidating the Altered Transcriptional Programs in Breast Cancer using Independent Component Analysis
Figure 2
(A) For each cohort and method, we give the pathway enrichment index, PEI, defined by the fraction of biological pathways (536 in total) found enriched in at least one component.
(B) For each cohort and method, we give the fraction of cancer-signalling and oncogenic pathways (14 in total) successfully mapped by the inferred components.
(C) For each cohort and method, we give the fraction of motif-regulatory gene sets (173 in total) captured by the inferred components.