CpG Island Mapping by Epigenome Prediction
Figure 1
This figure outlines the workflow used in this study to derive quantitative scores of CpG island strength, and to evaluate their performance as predictors of bona fide CpG islands. The arrows at the top describe the phases of the analysis, the cylinders correspond to input datasets (orange, blue, and brown cylinders) and results datasets (grey and green cylinders), and the rectangular boxes represent major computational steps. The sigmas in the calculation step 3 box stand for summation over the input. The figure is slightly simplified and focuses on a single CpG island map. In fact, the entire workflow was performed separately for three CpG island maps that differ in the repeat-exclusion strategy used (TJU, GGF, and GGM), with subsequent benchmarking of their performances (Figure 5).