Patterns of Mesenchymal Condensation in a Multiscale, Discrete Stochastic Model
Figure 7
In Vitro and Simulation Images for Stripe-Like Precartilage Condensations
(A) Stripe-like precartilage condensations.
(B) Spatial grid containing more than 6,000 cells produced by simulation showing stripes of fibronectin-producing differentiated cells (white), nondifferentiated cells (blue-gray), and empty space between cells (black).
(C) Spatial grid of same simulation as (B) showing fibronectin-rich stripes (black) produced by the differentiated cells.
(D) Spatial grid of same simulation as (B) showing activator concentrations at time slightly after the initial onset of cell differentiation. The color bar indicates the range, with magenta for high concentration and light blue for low concentration.