Increasing the Power to Detect Causal Associations by Combining Genotypic and Expression Data in Segregating Populations
Figure 4
Reconstruction accuracy with the genetic (dotted and solid lines) and without the genetic (dashed lines) information, using varying numbers of samples, and based on an overall genetic signal similar to that found in the BXD network, but with weaker interactions (see text for details)
(A) Reconstruction accuracy for the entire network.
(B) Reconstruction accuracy for the subnetwork comprising only the top layer of the network. The dotted lines reflect reconstructions that utilized cis QTL information as the only source of genetic information, whereas the solid lines reflect reconstructions that utilized all available genetic information.