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Potential Energy Landscape and Robustness of a Gene Regulatory Network: Toggle Switch

Figure 2

Probability C That Genes Are in the Active State as a Function of Xad = (g1 + g0)/2kA for a Symmetric Switch Showing the Bifurcation

Exact moment equation solutions are compared with Poisson ansatz solutions 0 < Xad(= g1/2) < 100 , kA = kB = 1, fA = fB = 0.5, hA = hB = fA/500, and gA0 = gB0 = 0.

Figure 2

doi: https://doi.org/10.1371/journal.pcbi.0030060.g002