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The Importance of Bottlenecks in Protein Networks: Correlation with Gene Essentiality and Expression Dynamics

Figure 4

Expression Dynamics of Hub–Nonbottlenecks and Hub–Bottlenecks

Histograms of the average correlation coefficient of the expression profile of any given gene with its direct interaction partners. Expression dynamics for all four categories of nodes are shown in Figure S7.

Figure 4

doi: https://doi.org/10.1371/journal.pcbi.0030059.g004