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Dynamic Simulations on the Arachidonic Acid Metabolic Network

Figure 2

Comparison of the Experimental Data and Computational Results

PMNs (20 × 106 cells/ml) were incubated at 37 °C with 10 μM A23187 (a calcium ionophore) (A) and 10 μM A23187 + 30 μM AA (B), respectively. The calculated results (line without star: red for LTB4 and blue for ω-LTB4) fit well to experimental data [22] (line with star: red for LTB4 and blue for ω-LTB4), considering experimental error.

Figure 2

doi: https://doi.org/10.1371/journal.pcbi.0030055.g002