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A Mathematical Model for Neutrophil Gradient Sensing and Polarization

Figure 7

The Effect of a Positive Feedback Loop Involving PIP3 on PIP3 (Blue) and Actin (Red) Back-to-Front Localization

The model was simulated with the autocatalytic PIP3 reaction (fb, solid lines) and without (dashed lines). The ordinate is molecular concentration and the abscissa is the position on the membrane (θ).

Figure 7

doi: https://doi.org/10.1371/journal.pcbi.0030036.g007