Repressor Dimerization in the Zebrafish Somitogenesis Clock
Figure 5
Simulated Translation Knockdown of her1 (A), her7 (B), and Combined her1 and her7 (C)
For single knockdowns, residual oscillations of diminished relative amplitude were observed, and stripe formation in anterior PSM was disrupted. For the combined knockdown, her1 and her7 were upregulated and did not oscillate in posterior PSM, but did oscillate in a salt-and-pepper pattern in anterior PSM.