Synonymous Substitution Rates Predict HIV Disease Progression as a Result of Underlying Replication Dynamics
Figure 4
Internal Synonymous and Nonsynonymous Divergence in Two Patients with Distinct Phenotypic Escape from Neutralizing Antibodies
Nonsynonymous and synonymous divergence is shown for complete env sequences serially sampled from patient 01–0083 (A), whose virus exhibited slow escape from neutralizing antibodies, and from patient 01–0127 (B), whose virus exhibited rapid escape from neutralizing antibodies [2]. The thick lines depict the mean divergence and the colored areas represent the 95% credibility intervals.