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Synonymous Substitution Rates Predict HIV Disease Progression as a Result of Underlying Replication Dynamics

Figure 2

Mean Synonymous and Nonsynonymous Divergence for Internal and Backbone Branches over the Course of HIV Infection in Nine Individuals

Patients with moderate and slow disease progression, categorized by progression time less than or greater than seven years [17], are shown in pink and blue, respectively. Individual patient numbers from Shankarappa et al. [14] are shown in circles, and progression times for each patient are indicated in italics.

Figure 2

doi: https://doi.org/10.1371/journal.pcbi.0030029.g002