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Dose Response Relationship in Anti-Stress Gene Regulatory Networks

Figure 8

Variation of Saturation Terms Affects the Length of Superlinear Controlled and Linear Uncontrolled Phases

(A) Lowering the dissociation constant Kd for transcription factor T binding to the gene promoter shortens the superlinear highly controlled phase.

(B) Lowering the Michaelis–Menten constant Km of enzyme G for clearance of Y shortens the linear uncontrolled phase.

Figure 8

doi: https://doi.org/10.1371/journal.pcbi.0030024.g008