Efficiency and Cost of Economical Brain Functional Networks
Figure 6
Anatomical Representation of Brain Functional Networks Highlighting Regional Effects of Age and Dopamine Receptor Antagonism
Brain functional networks for one young person following placebo (top row) and one old person following placebo (bottom row). These networks were constructed by thresholding the individual wavelet correlation matrices to derive sparse networks with equal cost, K ∼ 0.1: regional nodes are shown as dots or circles in a sagittal view of the right side of the brain; strong functional connections are shown as undirected edges between nodes. The size of regional nodes is proportional to the significance of age-related or drug-related reductions in regional efficiency: red nodes, efficiency reduced by older age; blue nodes, efficiency reduced by sulpiride; purple nodes, efficiency reduced by both older age and sulpiride. See Table 2 for anatomical detail concerning locations of significant difference in regional efficiency.