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Detecting Key Structural Features within Highly Recombined Genes

Figure 7

Module Networks of sof

(A) Shows the complete sof module network for 139 sof alleles harboring 97 modules. Modules are represented by nodes (depicted as circles), whereby the diameter of the node is proportional to the percent of alleles that harbor it. Node colors represent the number of correlation iterations used to define each node, as follows: blue (fewer than four iterations), green (four to eight iterations), and red (more than eight iterations). Arrows represent the connections between contiguous modules. Arrow thickness is proportional to the frequency with which each connection is observed in the dataset; for this diagram, one pixel is equivalent to ten connections. Tandem repeats of modules are not displayed in the network, but are shown in the module maps of each allele. The module maps of Figure 6 can be traced via arrows through the network graph.

(B) Depicts a simplified sof network, showing only those modules present in >10% of sof alleles (49 modules), and connections that occurred more than two times. The boxed area highlights a region of reduced recombination, and illustrates two discrete pathways of connections within the network.

Figure 7

doi: https://doi.org/10.1371/journal.pcbi.0030014.g007