Detecting Key Structural Features within Highly Recombined Genes
Figure 3
(A) Shows the complete pbp2x module network for 41 pbp2x alleles harboring 38 modules. Modules are represented by nodes (depicted as circles), whereby the diameter of the node is proportional to the percent of alleles that harbor it. Node colors represent the number of correlation iterations used to define each node, as follows: blue (more than four iterations), and green (four iterations). Arrows represent the connections between contiguous modules. Arrow thickness is proportional to the frequency with which each connection is observed in the dataset. The module maps of Figure 2 can be traced via arrows through the network graph.
(B) Depicts a simplified pbp2x network, showing only those modules present in >10% of pbp2x alleles (35 modules), and connections that occurred more than two times. Three connection pathways within the central portion of the module network are labeled I, II, and III (see Figure S4 for explanation).