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Emergent Dynamics of Thymocyte Development and Lineage Determination

Figure 5

Competition In Silico between CCR9−/− Cells and Wild-Type Cells

The three panels at the bottom, with context lines leading to the time-graph, show the ratios between the two cell populations developing over time. An initial peak of maturing wild-type cells is followed by a decrease and an eventual asymptotic ratio, as the buildup of random pressure of CCR9−/− cells eventually generates homeostasis. An asymptotic value of four wild-type thymocytes to every CCR9−/− thymocyte is reached. See text for further discussion.

Figure 5

doi: https://doi.org/10.1371/journal.pcbi.0030013.g005