Computational Model Explains High Activity and Rapid Cycling of Rho GTPases within Protein Complexes
Figure 7
Flux Diagrams for the Reduced Models of GEF–GAP (A) and M–GAP (B) Modules
Activation of RD by the GEF or by the GEF-effector complex (E*) is denoted as J1. Inactivation of RT by the GAP and its spontaneous hydrolysis are represented by fluxes J2 and J3, correspondingly. Activation of RD by M is represented by J4 in (B).