Detecting Statistically Significant Common Insertion Sites in Retroviral Insertional Mutagenesis Screens
Figure 5
Results from Simulation Experiments—Cross Scale True Positives and Deviations from CIS Center
(A) Average number of csTPs per artificially generated CIS. Significant errors are made for the borderline cases: the narrow CISs (500 bp), or broad CISs (80k bp) with relatively few insertions. The GKC outperforms the RKC and TKC for all simulated CISs.
(B) Average deviation of the detected CIS center from the actual simulated CIS center normalized on the simulated CIS width plus the scale parameter under consideration.