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Detecting Statistically Significant Common Insertion Sites in Retroviral Insertional Mutagenesis Screens

Figure 4

Results from Simulation Experiments—True and False Positives

(A,B) Results for the GKC applied to artificial data.

(C,D) Results for the TKC.

(E,F) Results for the RKC.

The horizontal solid lines in (A), (C), and (E) show the 5% significance level, the dotted lines show the average number of csFPs. The legend shows the different simulated CISs, stating the number of insertions NCIS that fall within the CIS of width WCIS.

Figure 4

doi: https://doi.org/10.1371/journal.pcbi.0020166.g004